Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide SNP-based linkage analysis for ADNSHL families identifies novel susceptibility loci with positive evidence for linkage.

Genes & genetic systems - 1 Jan 2011

Park Mi-Hyun, Park Hong-Joon, Kim Kwang-Joong, Woo Hae-Mi, Kim Hyung-Jin, Lee Jong-Young, Park Hyun-Young, Koo Soo Kyung

Abstract excerpt

The linkage search for susceptibility loci using SNP markers in hereditary hearing loss has proven challenging due to genetic heterogeneity. We conducted a genome-wide linkage analysis using high-density SNP markers in two Korean families (families coded SD-J and SR-167) with autosomal dominant non-syndromic hearing loss (ADNSHL). Evidence was found of linkage at 8q24.13~q24.3 and 10p11.21~q22.2 (LOD 3.01) in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomics
Share to Chromosomes, Human, Pair 10

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Computational Biology

Share to DNA Mutational Analysis

Share to Genes, Dominant

Share to Genetic Linkage

Share to Hearing Loss

Share to Republic of Korea

Source

Identifiers

PMID: 21670551
DOI: 10.1266/ggs.86.117

Genes

NPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide SNP-based linkage analysis for ADNSHL families identifies novel susceptibility loci with positive evidence for linkage.PMID 21670551Read ↗

SNP linkage analysis and whole exome sequencing identify a novel POU4F3 mutation in autosomal dominant late-onset nonsyndromic hearing loss (DFNA15).Semantic proximity Read ↗

Linkage and association studies in a Malaysian family with autosomal recessive non-syndromic hearing loss.Semantic proximity Read ↗

Novel autosomal recessive nonsyndromic hearing impairment locus DFNB90 maps to 7p22.1-p15.3.Semantic proximity Read ↗

Genome-widely significant evidence of linkage of schizophrenia to chromosomes 2p24.3 and 6q27 in an SNP-Based analysis of Korean families.Semantic proximity Read ↗

Pedigree-Based Gene Mapping Supports Previous Loci and Reveals Novel Suggestive Loci in Specific Language Impairment.Semantic proximity Read ↗

A high-density SNP genome-wide linkage scan in a large autism extended pedigree.Semantic proximity Read ↗

Gene localization in a Chinese family with autosomal dominant non-syndromic deafness.Semantic proximity Read ↗

Initial genome-wide scan for linkage with schizophrenia in the Japanese Schizophrenia Sib-Pair Linkage Group (JSSLG) families.Semantic proximity Read ↗

First confirmatory study on PTPRQ as an autosomal dominant non-syndromic hearing loss gene.Semantic proximity Read ↗

Support for schizophrenia susceptibility locus on chromosome 2q detected in a Swedish isolate using a dense map of microsatellites and SNPs.Semantic proximity Read ↗

Genome-wide and interaction linkage scan for nonsyndromic cleft lip with or without cleft palate in two multiplex families in Shenyang, China.Semantic proximity Read ↗

Genomewide linkage analysis to presbycusis in the Framingham Heart Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.