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MTNR1B Genetic Variability Is Associated with Gestational Diabetes in Czech Women

1 Jan 2014

Abstract excerpt

The gene MTNR1B encodes a receptor for melatonin. Melatonin receptors are expressed in human β-cells, which implies that genetic variants might affect glucose tolerance. Meta-analysis confirmed that the rs10830963 shows the most robust association. The aim of the study was to assess the rs10830963 in Czech GDM patients and controls and to study relations between the SNP and biochemical as well as anthropometric...

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PMID: 25132852
DOI: 10.1155/2014/508923

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