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Article

Knockdown of β-Catenin through shRNA cause a reversal of EMT and metastatic phenotypes induced by HIF-1α.

Cancer investigation - 1 Jul 2011

Zhao Jia-Hui, Luo Yong, Jiang Yong-Guang, He Da-Lin, Wu Chun-Ting

Abstract excerpt

OBJECTIVE: Wnt/β-catenin signaling pathway regulates pattern formation during embryogenesis as well as tumor progression. Numbers of studies suggest that this signaling pathway may play an important role in Epithelial-Mesenchymal transition (EMT), however, there was no evidence that Wnt/β-catenin signaling pathway directly controlled the EMT occurrence. Our previous research has successfully proved that...

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Source

Identifiers

PMID: 21649463
DOI: 10.3109/07357907.2010.512595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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