Article
Val1483Ile polymorphism in the fatty acid synthase gene was associated with depressive symptoms under the influence of psychological stress.
Journal of affective disorders - 1 Nov 2011
Tsuboi Hirohito, Sakakibara Hiroyuki, Yamakawa-Kobayashi Kimiko, Tatsumi Asami, Inamori Tomoko, Hamamoto Reiko, Suzuki Atsuko, Shimoi Kayoko
Abstract excerpt
BACKGROUND: To study the association between lipid-metabolism and depressive symptoms, genetic polymorphisms in serotonin transporter linked promoter region (5-HTTLPR) and fatty acid synthase gene (FASN) were investigated. METHOD: A cross-sectional study was conducted on 177 women (n = 166) and men (n = 15) recruited from workers in a hospital and nursing homes in Japan. Depressive symptoms were assessed by the...
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