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Article

To what extent are genetics clinically useful?

Best practice & research. Clinical gastroenterology - 1 Apr 2011

Vermeire Séverine

Abstract excerpt

The volume of research undertaken on the genetic susceptibility of inflammatory bowel diseases has been tremendous. International collaborative efforts which initiated in 1997 and have not stopped since, led to the identification at present of more than 100 IBD risk loci. Yet, only 25% of the genetic variance is explained. It is hypothesized that rare variants, other forms of genetic variation (copy number...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21640929
DOI: 10.1016/S1521-6918(11)70004-X

Genes

NOD2

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