Article
Disruption of the gene encoding subunit VI of yeast cytochrome bc1 complex causes respiratory deficiency of cells with reduced cytochrome c levels.
FEBS letters - 18 Jun 1990
Kim C H, Zitomer R S
Abstract excerpt
A double mutant of Saccharomyces cerevisiae, in which CYCL gene is deleted and the chromosomal copy of the 17 kDa protein gene is disrupted, has been constructed. This mutant cannot grow on nonfermentable carbon sources, but normal growth can be restored by complementation of either mutation with...
Topics
- Blotting, Southern
- Cytochrome Reductases
- Cytochrome c Group
- Genes, Fungal
- Genetic Complementation Test
- Macromolecular Substances
- Mitochondria
- Mutation
- NADH Dehydrogenase
- Oxidative Phosphorylation
- Oxygen Consumption
- Restriction Mapping
- Saccharomyces cerevisiae
- Succinates
