Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Simultaneous phenotyping and quantification of α-1-antitrypsin by liquid chromatography-tandem mass spectrometry.

Clinical chemistry - 1 Aug 2011

Chen Yuhong, Snyder Melissa R, Zhu Yi, Tostrud Linda J, Benson Linda M, Katzmann Jerry A, Bergen H Robert

Abstract excerpt

BACKGROUND: α-1-Antitrypsin (A1AT) deficiency results from a genetic disorder at 2 common loci. Diagnosis requires quantification of A1AT and subsequent identification of the specific variant. The current algorithm of laboratory testing for the diagnosis of A1AT deficiency uses a combination of q...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha 1-Antitrypsin
Share to alpha 1-Antitrypsin Deficiency
Share to Chromatography, Liquid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homozygote

Share to Immunoassay

Share to Isoelectric Focusing

Share to Nephelometry and Turbidimetry

Share to Tandem Mass Spectrometry

Source

Open in PubMed Open full text

Identifiers

PMID: 21636698
DOI: 10.1373/clinchem.2011.163006
PMCID: PMC3275912

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21636698-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Simultaneous phenotyping and quantification of α-1-antitrypsin by liquid chromatography-tandem mass spectrometry.PMID 21636698Read ↗

Liquid Chromatography-Tandem Mass Spectrometry-Based α1-Antitrypsin (AAT) Testing.Semantic proximity Read ↗

Alpha-1-Antitrypsin (A1AT) Proteotyping by LC-MS/MS.Semantic proximity Read ↗

Laboratory diagnosis of alpha1-antitrypsin deficiency.Semantic proximity Read ↗

Diagnosing Alpha-1-Antitrypsin Deficiency Using A PCR/Luminescence-Based Technology.Semantic proximity Read ↗

Diagnosis of alpha-1-antitrypsin deficiency: An algorithm of quantification, genotyping, and phenotyping.Semantic proximity Read ↗

State-of-the-art testing for alpha-1 antitrypsin deficiency.Semantic proximity Read ↗

A Library of Rare α1-Antitrypsin (AAT) Variant Phenotypes to Aid in the Diagnosis of AAT Deficiency.Semantic proximity Read ↗

Molecular diagnosis of alpha1-antitrypsin deficiency: A new method based on Luminex technology.Semantic proximity Read ↗

[Molecular diagnostics of alpha-1-antitrypsin deficiency in clinical practice].Semantic proximity Read ↗

Reference and interpretive ranges for α(1)-antitrypsin quantitation by phenotype in adult and pediatric populations.Semantic proximity Read ↗

Evaluation of an integrative diagnostic algorithm for the identification of people at risk for alpha1-antitrypsin deficiency.Semantic proximity Read ↗

Facilitating the laboratory diagnosis of α1-antitrypsin deficiency.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.