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Article

Differential resistance of mammalian sperm chromatin to oxidative stress as assessed by a two-tailed comet assay

5 May 2011

Abstract excerpt

Protamines of eutherian species are cysteine-rich molecules that become cross-linked by disulfide bonds during epididymal transit, whereas the protamines of most marsupial species lack cysteine residuals. The present study made use of the differences in protamine structure between eutherian and metatherian mammal spermatozoa to examine the comparative resistance of sperm DNA to oxidative damage in three eutherian...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 21635811
DOI: 10.1071/rd10269

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