In Nonfunctional Pituitary Adenomas, Estrogen Receptors and Slug Contribute to Development of Invasiveness

Abstract excerpt

CONTEXT: Clinical studies suggest that an imbalance in the actions of estrogen receptor (ER)-α and ERβ is associated with invasion of tumors of epithelial origin. Both ER have been detected in the pituitary adenomas (PA). Our previous study together with other reports suggests that an imbalance between ERα and ERβ contributes to the pathogenesis and biological behavior of PA including invasion. However, the roles...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Growth Hormone and Insulin-like Growth Factors
• Share to Pituitary Gland Disorders and Treatments
• Share to TGF-β signaling in diseases