Article
Polymorphisms at GSTM1 and GSTT1 gene loci and susceptibility to cervical cancer in Indian population.
Neoplasma - 1 Jan 2004
Sharma A, Sharma J K, Murthy N S, Mitra A B
Abstract excerpt
Multiple allelism at loci encoding detoxifying enzymes is associated with cancer risk. Glutathione S-transferase (GSTs) catalyzes the conjugation of glutathione to numerous potentially genotoxic compounds. This study evaluates the influence of genetic polymorphisms of GST M1 and GST T1 on susceptibility to cervical cancer. A multiplex polymerase chain reaction method was used to detect the presence or absence of...
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