Article
Enrichment of osteosarcoma stem cells by chemotherapy.
Chinese journal of cancer - 1 Jun 2011
Tang Qing-Lian, Liang Yi, Xie Xian-Biao, Yin Jun-Qiang, Zou Chang-Ye, Zhao Zhi-Qiang, Shen Jing-Nan, Wang Jin
Abstract excerpt
Osteosarcoma is the most common primary malignant bone cancer in children and adolescents. Emerging evidence has suggested that the capability of a tumor to grow is driven by a small subset of cells within a tumor, termed cancer stem cells (CSCs). Although several methods have been explored to identify or enrich CSCs in osteosarcoma, these methods sometimes seem impractical, and chemotherapy enrichment for CSCs...
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