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Article

Oligogenic heterozygosity in individuals with high-functioning autism spectrum disorders.

Human molecular genetics - 1 Sept 2011

Schaaf Christian P, Sabo Aniko, Sakai Yasunari, Crosby Jacy, Muzny Donna, Hawes Alicia, Lewis Lora, Akbar Humeira, Varghese Robin, Boerwinkle Eric, Gibbs Richard A, Zoghbi Huda Y

Abstract excerpt

Autism spectrum disorders (ASDs) are a heterogeneous group of neuro-developmental disorders. While significant progress has been made in the identification of genes and copy number variants associated with syndromic autism, little is known to date about the etiology of idiopathic non-syndromic autism. Sanger sequencing of 21 known autism susceptibility genes in 339 individuals with high-functioning, idiopathic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21624971
DOI: 10.1093/hmg/ddr243
PMCID: PMC3153303

Genes

CDKL5
HOXA1
TSC1
TSC2

Provenance

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