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Article

First evidence of genetic association between the MIF-173G/C single-nucleotide polymorphisms and polycystic ovary syndrome.

American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Nov 2011

Li Chao, Qiao Binglong, Zhan Ying, Qi Weihong, Chen Zi-Jiang

Abstract excerpt

PROBLEM: The purpose of this study was to investigate whether polymorphism of MIF gene is associated with PCOS. METHOD OF STUDY: The MIF-173G/C single-nucleotide polymorphism (SNP) was detected in 529 PCOS patients and 585 healthy female controls of Chinese Han ancestry. The association of the gene variants with clinical and metabolic parameters and hormone levels was investigated. RESULTS: The frequencies of...

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Source

Identifiers

PMID: 21623990
DOI: 10.1111/j.1600-0897.2011.01011.x

Genes

MIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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First evidence of genetic association between the MIF-173G/C single-nucleotide polymorphisms and polycystic ovary syndrome.PMID 21623990Read ↗

[Association between severe preeclampsia and single nucleotide polymorphism of macrophage migration inhibitory factors -173G/C].Semantic proximity Read ↗

Macrophage migration inhibitory factor promoter polymorphisms (-794 CATT 5-8 and -173 G>C): relationship with mRNA expression and soluble MIF levels in young obese subjects.Semantic proximity Read ↗

Association of MIF-173 gene polymorphism with inflammatory bowel disease in Chinese Han population.Semantic proximity Read ↗

Interleukin-6 -174 G/C promoter gene polymorphism and polycystic ovary syndrome: A cross sectional investigation in adult womenSemantic proximity Read ↗

-173G/C polymorphism in the promoter of MIF is associated with hepatitis B virus infection in a Chinese Han population.Semantic proximity Read ↗

Meta-analysis of the correlation between IL-6 -174 G/C polymorphism and polycystic ovarian syndrome.Semantic proximity Read ↗

The -173 G/C polymorphism of the MIF gene and inflammatory bowel disease risk: a meta-analysis.Semantic proximity Read ↗

Influence of the MIF polymorphism -173G > C on Turkish postmenopausal women with osteoporosis.Semantic proximity Read ↗

Evaluation of the association between GHR exon 3 polymorphism and polycystic ovary syndrome among Han Chinese women.Semantic proximity Read ↗

Relationship between MIF-173 G/C polymorphism and susceptibility to chronic hepatitis B and HBV-induced liver cirrhosis.Semantic proximity Read ↗

Microsatellite polymorphism in the fibrillin 3 gene and susceptibility to PCOS: a case-control study and meta-analysis.Semantic proximity Read ↗

Association study of HNF1A in women with polycystic ovary syndrome.Semantic proximity Read ↗

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