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An Epigenetic Marker Panel for Detection of Lung Cancer Using Cell-Free Serum DNA

24 May 2011

Abstract excerpt

PURPOSE: We investigated the feasibility of detecting aberrant DNA methylation of some novel and known genes in the serum of lung cancer patients. EXPERIMENTAL DESIGN: To determine the analytic sensitivity, we examined the tumor and the matched serum DNA for aberrant methylation of 15 gene promoters from 10 patients with primary lung tumors by using quantitative methylation-specific PCR. We then tested this...

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PMID: 21610147
DOI: 10.1158/1078-0432.ccr-10-3436

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