Article
Role of functional dopaminergic gene polymorphisms in the etiology of idiopathic intellectual disability.
Progress in neuro-psychopharmacology & biological psychiatry - 15 Aug 2011
Bhowmik Aneek Das, Chaudhury Subhramay, Dutta Samikshan, Shaw Jyoti, Chatterjee Arpita, Choudhury Arnab, Saha Amrita, Sadhukhan Dipanjana, Kar Turban, Sinha Swagata, Mukhopadhyay Kanchan
Abstract excerpt
Intellectual disability (ID) is of major concern throughout the world, though in ~40% of cases etiology remains unknown (idiopathic ID or IID). Cognitive impairment and behavioral problems are of common occurrence in these subjects and dopamine is known to play an important role in regulating these traits. In the present study the role of functional polymorphisms in three dopaminergic genes, dopamine receptor D4...
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