Article
Characterization by T1-oligonucleotide fingerprinting of three strains of human hepatitis A virus isolated in Italy.
European journal of epidemiology - 1 Mar 1990
Fiore L, De Paolis E, Novello F, Divizia M, Panà A
Abstract excerpt
Three human hepatitis A virus strains, all of them isolated in Italy but one acquired abroad, were analyzed by T1-RNAase oligonucleotide mapping and by monoclonal antibody neutralization. The variation among their genomes according to T1-maps was calculated to be about 9%, thus confirming the poor genomic variation assessed by nucleotide sequencing (1-10%). However T1-maps of these Italian isolates were different...
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