Corticotropin-releasing hormone augments natural killer cell activity through a naloxone-sensitive pathway.

doi:10.1016/0165-5728(90)90040-t

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Article

Corticotropin-releasing hormone augments natural killer cell activity through a naloxone-sensitive pathway.

Journal of neuroimmunology - 1 Jun 1990

Carr D J, DeCosta B R, Jacobson A E, Rice K C, Blalock J E

Abstract excerpt

Overnight treatment of murine leukocytes with corticotropin-releasing hormone (CRH) and arginine vasopressin enhances natural killer cell activity. Moreover, the opioid receptor antagonist, naloxone, as well as the delta-class opioid receptor antagonist, naltrindole, can block this effect. The re...

Topics

Animals
Corticotropin-Releasing Hormone
Female
In Vitro Techniques
Killer Cells, Natural
Kinetics
Macrophages
Mice
Mice, Inbred BALB C
Naloxone
Phenotype
Receptors, Opioid
Spleen
beta-Endorphin

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