Article
Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association Expert Panel on Familial Hypercholesterolemia.
Journal of clinical lipidology - 1 Jan 2000
Goldberg Anne C, Hopkins Paul N, Toth Peter P, Ballantyne Christie M, Rader Daniel J, Robinson Jennifer G, Daniels Stephen R, Gidding Samuel S, de Ferranti Sarah D, Ito Matthew K, McGowan Mary P, Moriarty Patrick M, Cromwell William C, Ross Joyce L, Ziajka Paul E
Abstract excerpt
The familial hypercholesterolemias (FH) are a group of genetic defects resulting in severe elevations of blood cholesterol levels and increased risk of premature coronary heart disease. FH is among the most commonly occurring congenital metabolic disorders. FH is a treatable disease. Aggressive lipid lowering is necessary to achieve the target LDL cholesterol reduction of at least 50% or more. Even greater target...
Topics
- Adult
- Anticholesteremic Agents
- Apolipoproteins B
- Child
- Coronary Disease
- Genetic Testing
- Homozygote
- Humans
- Hyperlipoproteinemia Type II