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Article

Na v1.4 and Na v1.5 are modulated differently during muscle immobilization and contractile phenotype conversion.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Aug 2011

Rannou Fabrice, Pennec Jean-Pierre, Morel Julie, Guéret Gildas, Leschiera Raphaël, Droguet Mickaël, Gioux Maxime, Giroux-Metges Marie-Agnès

Abstract excerpt

Muscle immobilization leads to modification in its fast/slow contractile phenotype. Since the properties of voltage-gated sodium channels (Na(v)) are different between "fast" and "slow" muscles, we studied the effects of immobilization on the contractile properties and the Na(v) of rat peroneus longus (PL). The distal tendon of PL was cut and fixed to the adjacent bone at neutral muscle length. After 4 or 8 wk of...

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Identifiers

PMID: 21596924
DOI: 10.1152/japplphysiol.01136.2010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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