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Article

Molecular characterisation of KIR2DS2*005, a fusion gene associated with a shortened KIR haplotype.

Genes and immunity - 1 Oct 2011

Ordóñez D, Gómez-Lozano N, Rosales L, Vilches C

Abstract excerpt

KIR2DS2 is an activating homologue of KIR2DL2, an inhibitory killer-cell immunoglobulin-like receptor (KIR) that surveys expression of major histocompatibility complex-C allotypes bearing a C1 epitope. We have studied here its allele KIR2DS2*005, which shows a hybrid structure-it is identical to other KIR2DS2 alleles in the ectodomain, but has transmembrane and cytoplasmic regions identical to those of...

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Identifiers

PMID: 21593779
DOI: 10.1038/gene.2011.35

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