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Article

Novel and conserved protein macoilin is required for diverse neuronal functions in Caenorhabditis elegans.

PLoS genetics - 1 May 2011

Miyara Akiko, Ohta Akane, Okochi Yoshifumi, Tsukada Yuki, Kuhara Atsushi, Mori Ikue

Abstract excerpt

Neural signals are processed in nervous systems of animals responding to variable environmental stimuli. This study shows that a novel and highly conserved protein, macoilin (MACO-1), plays an essential role in diverse neural functions in Caenorhabditis elegans. maco-1 mutants showed abnormal behaviors, including defective locomotion, thermotaxis, and chemotaxis. Expression of human macoilin in the C. elegans...

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PMID: 21589894
DOI: 10.1371/journal.pgen.1001384
PMCID: PMC3093358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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