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Article

Leptin, leptin gene and leptin receptor gene polymorphism in heart failure with preserved ejection fraction.

Heart and vessels - 1 May 2012

Abd El-Aziz Tarek A, Mohamed Randa H, Mohamed Rasha H, Pasha Heba F

Abstract excerpt

Heart failure with a normal ejection fraction (HFNEF) is common in obesity and coronary artery disease (CAD). Both ischemia and reperfusion induce leptin (LEP) and leptin receptor (LEPR) gene expression. We aimed to investigate the possible associations of serum leptin, leptin gene and leptin receptor gene polymorphism with HFNEF in patients with CAD. 100 Egyptian CAD patients with HFNEF and 100 healthy subjects...

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Identifiers

PMID: 21584748
DOI: 10.1007/s00380-011-0152-2

Genes

LEPR
CAD
LEP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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