Association study between the -866G/A polymorphism in the promoter of uncoupling protein-2 gene and polycystic ovary syndrome.

doi:10.3892/mmr.2011.497

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Article

Association study between the -866G/A polymorphism in the promoter of uncoupling protein-2 gene and polycystic ovary syndrome.

Molecular medicine reports - 1 Jan 2000

Kim Jun-Hyun, Li Lan, Yun Ji-Hyun, Choi Bum-Chae, Baek Kwang-Hyun

Abstract excerpt

Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism, chronic oligoanovulation and insulin resistance. A number of women with PCOS are obese and exhibit abnormal phenotypes, including high levels of androgens, an irregular menstrual cycle and increased hair growth. Studies on obese PCOS patients have proven the crucial role that obesity plays in insulin resistance and hyperinsulinemia....

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PMID: 21584501
DOI: 10.3892/mmr.2011.497

Genes

UCP2

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