Article
Attenuation of febrile seizures in epileptic chicks by N-methyl-D-aspartate receptor antagonists.
Canadian journal of physiology and pharmacology - 1 Jan 1990
Pedder S C, Wilcox R I, Tuchek J M, Johnson D D, Crawford R D
Abstract excerpt
Experimental febrile seizures can be evoked in epileptic chicks by elevation of their body temperature. Both competitive N-methyl-D-aspartate (NMDA) receptor antagonists [(3-(+/- )2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP), DL-2-amino-7-phosphosphonoheptanoic acid (APH), DL-2-amino-5-phosphonovaleric acid (APV), D-alpha-aminoadipic acid (AAA), and DL-alpha, epsilon-diaminopimelic acid (DAP)] and the...
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