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Article

Definition of the sequence requirements for binding of the EBNA-1 protein to its palindromic target sites in Epstein-Barr virus DNA.

Journal of virology - 1 May 1990

Ambinder R F, Shah W A, Rawlins D R, Hayward G S, Hayward S D

Abstract excerpt

Interaction between the trans-acting DNA-binding protein EBNA-1 and cis-acting sequences in the ori-P region of Epstein-Barr virus DNA is required for maintenance of the viral plasmid state in latently infected B cells and is involved in the regulation of transcription during latency. In the Epstein-Barr virus genome, a total of 26 EBNA-1-binding sites occur within three clustered loci referred to as the family...

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Identifiers

PMID: 2157891
DOI: 10.1128/JVI.64.5.2369-2379.1990
PMCID: PMC249398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Definition of the sequence requirements for binding of the EBNA-1 protein to its palindromic target sites in Epstein-Barr virus DNA.PMID 2157891Read ↗

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Sequence requirements of the Epstein-Barr virus latent origin of DNA replicationSemantic proximity Read ↗

Two Domains of the Epstein-Barr Virus Origin DNA-binding Protein, EBNA1, Orchestrate Sequence-specific DNA BindingSemantic proximity Read ↗

EBNA1 can link the enhancer element to the initiator element of the Epstein-Barr virus plasmid origin of DNA replicationSemantic proximity Read ↗

Replication from <i>oriP</i> of Epstein-Barr Virus Requires Exact Spacing of Two Bound Dimers of EBNA1 Which Bend DNASemantic proximity Read ↗

The enhancer factor R of Epstein-Barr virus (EBV) Is a sequence-specific DNA binding proteinSemantic proximity Read ↗

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Multiple regions within EBNA1 can link DNAsSemantic proximity Read ↗

The Linking Regions of EBNA1 Are Essential for Its Support of Replication and TranscriptionSemantic proximity Read ↗

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