Article
Phosphorylation of the yeast γ-tubulin Tub4 regulates microtubule function.
PloS one - 5 May 2011
Lin Tien-chen, Gombos Linda, Neuner Annett, Sebastian Dominik, Olsen Jesper V, Hrle Ajla, Benda Christian, Schiebel Elmar
Abstract excerpt
The yeast γ-tubulin Tub4 is assembled with Spc97 and Spc98 into the small Tub4 complex. The Tub4 complex binds via the receptor proteins Spc72 and Spc110 to the spindle pole body (SPB), the functional equivalent of the mammalian centrosome, where the Tub4 complex organizes cytoplasmic and nuclear microtubules. Little is known about the regulation of the Tub4 complex. Here, we isolated the Tub4 complex with the...
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