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Article

11p14.1 microdeletions associated with ADHD, autism, developmental delay, and obesity.

American journal of medical genetics. Part A - 1 Jun 2011

Shinawi Marwan, Sahoo Trilochan, Maranda Bruno, Skinner S A, Skinner Cindy, Chinault Craig, Zascavage Roxanne, Peters Sarika U, Patel Ankita, Stevenson Roger E, Beaudet Arthur L

Abstract excerpt

Genomic copy number imbalances are being increasingly identified as an important cause of intellectual disability and behavioral abnormalities. The typical deletion in WAGR syndrome encompasses the PAX6 and WT1 genes, but larger deletions have been associated with neurobehavioral abnormalities and obesity. We identified four patients with overlapping interstitial deletions on 11p14.1 and extending telomeric to...

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Topics

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Share to Attention Deficit Disorder with Hyperactivity
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Deletion

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Share to Chromosomes, Human, Pair 11

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Share to In Situ Hybridization, Fluorescence

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Source

Identifiers

PMID: 21567907
DOI: 10.1002/ajmg.a.33878

Genes

BDNF
PAX6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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