Article
Circulating cell-free nucleic acids: promising biomarkers of hepatocellular carcinoma.
Seminars in oncology - 1 Aug 2012
Zhou Jian, Shi Ying-Hong, Fan Jia
Abstract excerpt
Hepatocellular carcinoma (HCC) is considered to be a fatal disease because of its late diagnosis, underlying liver disease, and refractoriness to systemic treatments. Biomarkers with high sensitivity and specificity that are minimally invasive, reproducible, and easily available have important clinical utility for early diagnosis, prognostication, and pharmacodynamics evaluation. Until now, most of the...
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