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Article

EGFR signaling regulates tumor cell migration in craniopharyngiomas.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2011

Hölsken Annett, Gebhardt Matthias, Buchfelder Michael, Fahlbusch Rudolf, Blümcke Ingmar, Buslei Rolf

Abstract excerpt

PURPOSE: Constitutive Wnt signaling caused by mutations in the β-catenin gene is a molecular hallmark of adamantinomatous craniopharyngiomas (adaCP) and promotes infiltration into adjacent brain tissue. Herein, we studied the pathogenic role of epidermal growth factor receptor (EGFR) activation i...

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Source

Identifiers

PMID: 21562037
DOI: 10.1158/1078-0432.CCR-10-2811

Genes

EGFR
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21562037-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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