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Article

Copy number variants in patients with severe oligozoospermia and Sertoli-cell-only syndrome.

PloS one - 29 Apr 2011

Tüttelmann Frank, Simoni Manuela, Kliesch Sabine, Ledig Susanne, Dworniczak Bernd, Wieacker Peter, Röpke Albrecht

Abstract excerpt

A genetic origin is estimated in 30% of infertile men with the common phenotypes of oligo- or azoospermia, but the pathogenesis of spermatogenic failure remains frequently obscure. To determine the involvement of Copy Number Variants (CNVs) in the origin of male infertility, patients with idiopathic severe oligozoospermia (N = 89), Sertoli-cell-only syndrome (SCOS, N = 37)) and controls with normozoospermia...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21559371
DOI: 10.1371/journal.pone.0019426
PMCID: PMC3084853

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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