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Article

Iron-related MRI images in patients with pantothenate kinase-associated neurodegeneration (PKAN) treated with deferiprone: results of a phase II pilot trial.

Movement disorders : official journal of the Movement Disorder Society - 1 Aug 2011

Zorzi Giovanna, Zibordi Federica, Chiapparini Luisa, Bertini Enrico, Russo Lidia, Piga Antonio, Longo Filomena, Garavaglia Barbara, Aquino Domenico, Savoiardo Mario, Solari Alessandra, Nardocci Nardo

Abstract excerpt

BACKGROUND: The safety and efficacy of the oral iron-chelating agent deferiprone on magnetic resonance pallida iron concentration and on clinical status were investigated in 10 patients affected by pantothenate kinase-associated neurodegeneration. METHODS: Nine patients (age range, 7-39 years) completed the study. RESULTS: A significant median reduction in globus pallidus iron content as assessed by T2*...

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PMID: 21557313
DOI: 10.1002/mds.23751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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