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Article

MR relaxometry and 1H MR spectroscopy for the determination of iron and metabolite concentrations in PKAN patients.

European radiology - 1 May 2005

Hájek Milan, Adamovicová Miriam, Herynek Vít, Skoch Antonín, Jírů Filip, Krepelová Anna, Dezortová Monika

Abstract excerpt

The influence of iron deposits on T2 values and the content of metabolites in the brain of three patients with DNA proved pantothenate kinase-associated neurodegeneration (PKAN, formerly Hallervorden-Spatz syndrome) was studied. An eye-of-the-tiger sign, a typical MR finding for PKAN, was observed in two patients with the same mutation. A hypointensive lesion in a whole globus pallidus was observed in the third...

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Source

Identifiers

PMID: 15565311
DOI: 10.1007/s00330-004-2553-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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