Rapid microfluidic perfusion enabling kinetic studies of lipid ion channels in a bilayer lipid membrane chip.

Abstract excerpt

There is growing recognition that lipids play key roles in ion channel physiology, both through the dynamic formation and dissolution of lipid ion channels and by indirect regulation of protein ion channels. Because existing technologies cannot rapidly modulate the local (bio)chemical conditions at artificial bilayer lipid membranes used in ion channel studies, the ability to elucidate the dynamics of these...

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