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Article

A novel homozygous missense mutation in WNT10B in familial split-hand/foot malformation.

Clinical genetics - 1 Jul 2012

Khan S, Basit S, Zimri F K, Ali N, Ali G, Ansar M, Ahmad W

Abstract excerpt

Split-hand/foot malformation (SHFM) is a rare limb developmental malformation, characterized by variable degree of median clefts of hands and feet due to the absence of central rays of extremities. To date, six different forms of SHFM have been described. Four of these SHFM1, SHFM3, SHFM4 and SHFM5 show autosomal dominant, SHFM6 autosomal recessive and SHFM2 X-linked pattern of inheritance. In this study a large...

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Share to Abnormalities, Multiple
Share to Chromosomes, Human, Pair 12
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Foot Deformities, Congenital

Share to Genes, Recessive

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Identifiers

PMID: 21554266
DOI: 10.1111/j.1399-0004.2011.01698.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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