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Cell-to-cell HIV-1 spread and its implications for immune evasion

1 Mar 2009

Abstract excerpt

PURPOSE OF REVIEW: The ability of HIV-1 to move between cells via direct cell-cell transmission is currently receiving a lot of attention. This review will discuss cell-cell spread of HIV-1 in terms of cellular and molecular mechanisms and will consider the evidence for immune and therapeutic evasion. RECENT FINDINGS: Recent studies relating to the cell biology of HIV-1 cell-cell spread have sparked considerable...

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PMID: 19339954
DOI: 10.1097/coh.0b013e328322f94a

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