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Article

NARP mutation and mtDNA depletion trigger mitochondrial biogenesis which can be modulated by selenite supplementation.

The international journal of biochemistry & cell biology - 1 Aug 2011

Wojewoda Marta, Duszyński Jerzy, Szczepanowska Joanna

Abstract excerpt

The importance of mitochondrial biogenesis in the pathogenesis of mitochondrial diseases has been widely recognised but little is known about it with regard to NARP (Neuropathy, Ataxia and Retinitis Pigmentosa) syndrome. Since such knowledge would contribute to the understanding of the pathogenesis of this disease, we designed a study to provide comprehensive overview of mitochondrial biogenesis in cybrid cells...

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Source

Identifiers

PMID: 21550418
DOI: 10.1016/j.biocel.2011.04.011

Genes

NRF1
PGC
TFAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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