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Article

A hybrid model to study pathological mutations of the human ADP/ATP carriers.

Biochimie - 1 Sept 2011

Thomas Amandine, Rey Martial, Aubry Laurence, Pelosi Ludovic

Abstract excerpt

The adenine nucleotide carrier (Ancp) plays an essential role in the metabolism of cellular energy by catalyzing the transport of ADP and ATP across the inner mitochondrial membrane. Previous reports have indicated that mutations in the HANC1 gene, encoding the muscle isoform of human Ancp (HAnc1p), are directly involved in several diseases, including autosomal dominant progressive external ophthalmoplegia and...

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PMID: 21549803
DOI: 10.1016/j.biochi.2011.04.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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