Article
Subunits of the yeast mitochondrial ADP/ATP carrier: cooperation within the dimer.
Biochemistry - 15 Nov 2005
Postis Vincent, De Marcos Lousa Carine, Arnou Bertrand, Lauquin Guy J-M, Trézéguet Véronique
Abstract excerpt
The mitochondrial ADP/ATP carrier, or Ancp, is a member of the mitochondrial carrier family (MCF). It exchanges ADP and ATP between matrix and intermembrane space. It is postulated from numerous experiments that the inactive Ancp bound to one of its inhibitors (CATR or BA) is a dimer, and it is inferred that the active unit is a dimer, too. However, the structure of beef Ancp bound to CATR obtained at high...
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