Article
Arabidopsis Argonaute 2 regulates innate immunity via miRNA393(∗)-mediated silencing of a Golgi-localized SNARE gene, MEMB12.
Molecular cell - 6 May 2011
Zhang Xiaoming, Zhao Hongwei, Gao Shang, Wang Wei-Chi, Katiyar-Agarwal Surekha, Huang Hsien-Da, Raikhel Natasha, Jin Hailing
Abstract excerpt
Argonaute (AGO) proteins are critical components of RNA silencing pathways that bind small RNAs and mediate gene silencing at their target sites. We found that Arabidopsis AGO2 is highly induced by the bacterial pathogen Pseudomonas syringae pv. tomato (Pst). Further genetic analysis demonstrated that AGO2 functions in antibacterial immunity. One abundant species of AGO2-bound small RNA is miR393b(∗), which...
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