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Article

Quantitative differential proteomics of cystic fibrosis cell models by SILAC (stable isotope labelling in cell culture).

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011

Guerrera Ida Chiara, Ollero Mario, Vieu Diane-Lore, Edelman Aleksander

Abstract excerpt

Differential proteomics represents an enticing strategy to unmask the proteins involved in CF pathogenesis and to discover potential therapeutic targets and/or markers of disease progression. Quantitative proteomics is possible nowadays owing to the recent progress in protein labelling and/or in label-free approaches, combined to sensitive detection by mass spectrometry (MS). In this chapter, we present one...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21547735
DOI: 10.1007/978-1-61779-120-8_13

Genes

CFTR

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