Combined Deletions of <i>pfhrp2</i> and <i>pfhrp3</i> Genes Result in Plasmodium falciparum Malaria False-Negative Rapid Diagnostic Test

Abstract excerpt

We report a case of misdiagnosis of Plasmodium falciparum malaria from Brazil with negative PfHRP2-based rapid diagnostic tests (RDTs), leading to inappropriate case management. Genetic tests showed the deletion of both pfhrp2 and pfhrp3 genes. The detection of two distinct P. falciparum target antigens is then advisable.

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Invertebrate Immune Response Mechanisms
• Share to Malaria Research and Control
• Share to Mosquito-borne diseases and control