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Article

Pfhrp2/3 gene deletion and genetic variation in PfHRP2-based RDTs with P. falciparum positive samples from India and its implication on malaria control.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Apr 2022

Kumari Ms Sarita, Sharma Supriya, Bhardwaj Nitin, Kumar Sandeep, Ahmed Md Zohaib, Pande Veena, Anvikar Anupkumar R

Abstract excerpt

BACKGROUND: Recent studies have documented Pfhrp2/3 gene deletion globally as one of the biological threats in the fight against malaria. For malaria diagnosis, PfHRP2 based RDTs are most widely used in India, and performance of these RDTs are affected by deleted Pfhrp2/3 gene in Plasmodium falciparum. This study was planned to confirm Pfhrp2/3 gene deletion incidences and genetic variation in PfHRP2-based RDT...

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PMID: 35114396
DOI: 10.1016/j.meegid.2022.105232

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