Article
An association between alpha 1-antitrypsin phenotype and chronic liver disease.
Human genetics - 1 Jan 1990
Kishimoto Y, Yamada S, Hirayama C
Abstract excerpt
The phenotypes of alpha-1-antitrypsin have been analyzed by isoelectric focusing on polyacrylamide gels in 232 healthy Japanese blood donors and in 240 Japanese patients with chronic liver diseases: 69 with chronic active hepatitis, 122 with liver cirrhosis, 41 with hepatocellular carcinoma and 8 with primary biliary cirrhosis. The liver cirrhosis patients had a gene frequency of 0.07 for P1*M3, which was...
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