Article
Shift work in nurses: contribution of phenotypes and genotypes to adaptation.
PloS one - 13 Apr 2011
Gamble Karen L, Motsinger-Reif Alison A, Hida Akiko, Borsetti Hugo M, Servick Stein V, Ciarleglio Christopher M, Robbins Sam, Hicks Jennifer, Carver Krista, Hamilton Nalo, Wells Nancy, Summar Marshall L, McMahon Douglas G, Johnson Carl Hirschie
Abstract excerpt
BACKGROUND: Daily cycles of sleep/wake, hormones, and physiological processes are often misaligned with behavioral patterns during shift work, leading to an increased risk of developing cardiovascular/metabolic/gastrointestinal disorders, some types of cancer, and mental disorders including depression and anxiety. It is unclear how sleep timing, chronotype, and circadian clock gene variation contribute to...
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