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Article

Evaluation of 4-[18F]fluorobenzoyl-FALGEA-NH2 as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer.

Nuclear medicine and biology - 1 May 2011

Denholt Charlotte Lund, Binderup Tina, Stockhausen Marie-Thérése, Poulsen Hans Skovgaard, Spang-Thomsen Mogens, Hansen Paul Robert, Gillings Nic, Kjær Andreas

Abstract excerpt

INTRODUCTION: This study describes the radiosynthesis, in vitro and in vivo evaluation of the novel small peptide radioligand, 4-[(18)F]fluorobenzoyl-Phe-Ala-Leu-Gly-Glu-Ala-NH(2,) ([(18)F]FBA-FALGEA-NH(2)) as a positron emission tomography (PET) tracer for imaging of the cancer specific epidermal growth factor receptor (EGFR) variant III mutation, EGFRvIII. METHODS: For affinity, stability and PET measurements,...

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Identifiers

PMID: 21531288
DOI: 10.1016/j.nucmedbio.2010.11.003

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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