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Article

Neuronal Autophagy as a Mediator of Life and Death

27 Apr 2011

Abstract excerpt

Autophagy is a cellular mechanism for degrading proteins and organelles. It was first described as a physiological process essential for cellular health and survival, and this is its role in most cells. However, it can also be a mediator of cell death, either by the triggering of apoptosis or by an independent "autophagic" cell death mechanism. This duality is important in the central nervous system, where the...

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PMID: 21525331
DOI: 10.1177/1073858411404948

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