Article
Genetic study of two single nucleotide polymorphisms within corresponding microRNAs and susceptibility to tuberculosis in a Chinese Tibetan and Han population.
Human immunology - 1 Jul 2011
Li Dongdong, Li Dingdong, Wang Tingting, Song Xingbo, Qucuo MeiLang, Yang Bin, Zhang Junlong, Wang Jun, Ying Binwu, Tao Chuanmin, Wang Lanlan
Abstract excerpt
MicroRNAs (miRNA) are thought to play important roles in the pathogenesis of diseases. Single nucleotide polymorphisms (SNPs) within miRNAs can change their characteristics via altering their target selection and/or expression, resulting in functional and/or phenotypic changes. We decided to investigate the genetic association with pulmonary tuberculosis with 2 nucleotide variations within corresponding microRNAs...
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