Association of Rsa polymorphism of the estrogen receptor-β gene with rheumatoid arthritis.

doi:10.1007/s00296-011-1947-2

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Article

Association of Rsa polymorphism of the estrogen receptor-β gene with rheumatoid arthritis.

Rheumatology international - 1 Jul 2012

Sato Hiromi, Ito Ayano, González-Canga Aránzazu, Okuzawa Hiroko, Ugai Kanako, Suzuki Masahiko, Namiki Takao, Ueno Koichi

Abstract excerpt

To investigate the possible influence of the single nucleotide polymorphism (SNP) of the estrogen receptor-β gene, rs1256049 (Rsa) in exon 5, on the frequency of rheumatoid arthritis (RA), 263 RA patients and 174 control subjects with osteoarthritis (OA) were recruited. Rsa polymorphism was detected using a PCR-RFLP, Polymerase Chain Reaction-Restriction Fragment Length Polymorphism method. The occurrence of both...

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PMID: 21523342
DOI: 10.1007/s00296-011-1947-2

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