Article
An E3 ligase complex regulates SET-domain polycomb group protein activity in Arabidopsis thaliana.
Proceedings of the National Academy of Sciences of the United States of America - 10 May 2011
Jeong Cheol Woong, Roh Hyungmin, Dang Tuong Vi, Choi Yang Do, Fischer Robert L, Lee Jong Seob, Choi Yeonhee
Abstract excerpt
Transcriptional repression via methylation of histone H3 lysine 27 (H3K27) by the polycomb repressive complex 2 (PRC2) is conserved in higher eukaryotes. The Arabidopsis PRC2 controls homeotic gene expression, flowering time, and gene imprinting. Although downstream target genes and the regulatory mechanism of PRC2 are well understood, much less is known about the significance of posttranslational regulation of...
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