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Article

Variants modulating the expression of a chromosome domain encompassing PLAG1 influence bovine stature.

Nature genetics - 1 May 2011

Karim Latifa, Takeda Haruko, Lin Li, Druet Tom, Arias Juan A C, Baurain Denis, Cambisano Nadine, Davis Stephen R, Farnir Frédéric, Grisart Bernard, Harris Bevin L, Keehan Mike D, Littlejohn Mathew D, Spelman Richard J, Georges Michel, Coppieters Wouter

Abstract excerpt

We report mapping of a quantitative trait locus (QTL) with a major effect on bovine stature to a ∼780-kb interval using a Hidden Markov Model-based approach that simultaneously exploits linkage and linkage disequilibrium. We re-sequenced the interval in six sires with known QTL genotype and identified 13 clustered candidate quantitative trait nucleotides (QTNs) out of >9,572 discovered variants. We eliminated...

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Source

Identifiers

PMID: 21516082
DOI: 10.1038/ng.814

Genes

CHCHD7
PLAG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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